Ma. Belmonte et al., AVASCULAR NECROSIS OF BONE IN HUMAN-IMMUNODEFICIENCY-VIRUS INFECTION AND ANTIPHOSPHOLIPID ANTIBODIES, Journal of rheumatology, 20(8), 1993, pp. 1425-1428
We describe 3 cases of human immunodeficiency virus (HIV) infected pat
ients with antiphospholipid antibodies (aPL) in serum who developed av
ascular necrosis (AVN), an association that to our knowledge, has rare
ly been described. Given that the 3 patients had stopped their intrave
nous drug addiction 2 years before the clinical picture appeared, and
none had any known risk factors for developing AVN, there may be an as
sociation, perhaps fortuitous, between HIV infection, the presence of
aPL and the development of AVN.