Impedance cardiography has been used over the last 30 years to measure
stroke volume on a beat-by-beat basis. Cardiac output has been succes
sfully measured with either upper or lower body exercise during light
or moderate workloads. With strenuous exercise, movement artifacts sev
erely limit the acquisition of a quality impedance cardiogram. Advance
s in computer technology and signal conditioning techniques have creat
ed the next generation of impedance cardiograph systems. The purpose o
f this study was to evaluate such a system, the noninvasive continuous
cardiac output monitor (NCCOM3-R7), at rest and during submaximal upr
ight cycle exercise. In addition, the relationships between thoracic i
mpedance (Z(o)), first derivative of the change in thoracic impedance
(dZ/dt) and posture were evaluated using the NCCOM3-R7 and the Minneso
ta impedance cardiograph 304B (MIC). Twenty-eight healthy men and wome
n participated. The Z(o) progressively increased when moving from the
supine to seated to standing position with both instruments. However,
the NCCOM3-R7 yielded lower Z(o) values and higher dZ/dt values compar
ed with the MIC for all postures. Z(o) and dZ/dt values appear to be d
ependent upon factors such as posture, gender, electrical current, and
characteristics of the instrumentation. Exercise cardiac output value
s seemed reasonable for most subjects, although population subsets exi
st where the accuracy must be questioned. The general consensus suppor
ted by the impedance literature and reaffirmed by the present observat
ions is that impedance cardiography provides a reasonable estimate of
the directional changes in stroke volume and cardiac output during exe
rcise and can be used to monitor changes in thoracic fluid balance. As
this technology evolves and is further refined, it will undoubtedly p
lay an increasing role in environmental medicine, exercise stress test
ing, cardiac rehabilitation, and sports medicine.