L. Kanerva et al., OCCUPATIONAL ALLERGIC CONTACT-DERMATITIS CAUSED BY DIETHYLENETRIAMINEIN CARBONLESS COPY PAPER, Contact dermatitis, 29(3), 1993, pp. 147-151
Carbonless copy paper, or 'no carbon required' (NCR) paper, has often
been implicated as the cause of skin, respiratory, or general symptoms
, but allergy has been verified in only a few cases. A 43-year-old mac
hinist whose work involved the manufacture of NCR paper developed occu
pational dermatitis on the hands. On patch testing, both the NCR paper
and 1 of the chemicals used to produce the microcapsules of the NCR p
aper, namely diethylenetriamine (DETA), provoked an allergic reaction.
Analysis of the paper showed that it contained enough DETA to induce
allergic contact dermatitis. People who handle NCR paper and develop s
ymptoms of contact dermatitis should be patch tested with DETA.