Arterial injuries of the thoracic outlet are complex and require a pre
cise plan for adequate management and prompt exposure of injured vesse
ls. Our 10-year experience with 28 such injuries is reviewed. Arteriog
raphy was performed whenever possible in stable patients (15) and aide
d in planning the operative approach. Unstable patients with active bl
eeding, pulsatile or expanding hematoma, or pulse deficit were taken t
o the operating room without delay. A thoracic approach was required i
n 15 patients, and the exposure was extrathoracic in 12 patients. Airw
ay was secured with liberal use of emergency endotracheal intubation (
16 patients). Primary repair was possible in 16 patients, with graftin
g performed in eight and ligation in three. One vertebral artery injur
y was successfully controlled with embolization. Venous injuries were
repaired in six patients and ligation was necessary in eight; there wa
s no significant morbidity. Two patients died in this series from comp
lications of severe hemorrhage. Significant morbidity was encountered
from associated neurologic injuries in 15 patients. Stroke was evident
in two patients, both of whom were moribund preoperatively. Proximal
subclavian artery injuries were particularly more problematic and freq
uently required an interim anterior thoracotomy for early control of e
xsanguinating hemorrhage. Our philosophy in the management of these in
juries and choices of exposure are discussed in detail.