ANTIFUNGAL AGENTS .6. IN-VITRO ANTIFUNGAL ACTIVITIES OF HALOBENZOYL ESTERS OF -IMIDAZAOL-1-YLMETHYL)-1,3-DIOXOLAN-4-YL]CARBINOLS AND H-IMIDAZOL-1-YLMETHYL)-1,3-DIOXOLAN-4-YL]CARBINOLS

Authors
STEFANCICH G SILVESTRI R PAGNOZZI E ARTICO M RETICO A APUZZO G SIMONETTI N
Citation
G. Stefancich et al., ANTIFUNGAL AGENTS .6. IN-VITRO ANTIFUNGAL ACTIVITIES OF HALOBENZOYL ESTERS OF -IMIDAZAOL-1-YLMETHYL)-1,3-DIOXOLAN-4-YL]CARBINOLS AND H-IMIDAZOL-1-YLMETHYL)-1,3-DIOXOLAN-4-YL]CARBINOLS, Il Farmaco, 48(8), 1993, pp. 1103-1112
Citations number
9
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
Il Farmaco → ACNP
ISSN journal
0014827X
Volume
48
Issue
8
Year of publication
1993
Pages
1103 - 1112
Database
ISI
SICI code
0014-827X(1993)48:8<1103:AA.IAA>2.0.ZU;2-Z
Abstract
The synthesis and the in vitro antifungal activities against Candida a lbicans and Candida spp of a number of halobenzoyl esters of cis- and H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]carbinols is reported. Some n ew imidazoles were found more active than ketoconazole and sometimes a s potent as bifonazole against Candida albicans. All derivatives were found scarcely active against Candida spp.