STEREOSELECTIVE ADDITION OF 2-AMINOTHIOPHENOL TO ALPHA-ALKOXYCINNAMICACID-DERIVATIVES - ALTERNATIVE SYNTHESIS OF (+ -)-DILTIAZEM/

Authors
MIYATA O SHINADA T NAITO T NINOMIYA I DATE T OKAMURA K
Citation
O. Miyata et al., STEREOSELECTIVE ADDITION OF 2-AMINOTHIOPHENOL TO ALPHA-ALKOXYCINNAMICACID-DERIVATIVES - ALTERNATIVE SYNTHESIS OF (+ -)-DILTIAZEM/, Tetrahedron, 49(36), 1993, pp. 8119-8128
Citations number
21
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
49
Issue
36
Year of publication
1993
Pages
8119 - 8128
Database
ISI
SICI code
0040-4020(1993)49:36<8119:SAO2TA>2.0.ZU;2-S
Abstract
A stereocontrolled synthesis of (+/-)-diltiazem by applying nucleophil ic addition of 2-aminothiophenol to alpha-alkoxycinnamic acid derivati ves is described.