Ij. Witterick et al., INCIDENCE AND TYPES OF NON-PALPABLE THYROID-NODULES IN THYROIDS REMOVED FOR PALPABLE DISEASE, Journal of otolaryngology, 22(4), 1993, pp. 294-300
The purpose of this study was to determine the number, size and types
of non-palpable and ultrasound undected thyroid nodules in thyroid gla
nds removed for a single palpable nodule. Twenty patients undergoing p
artial (hemi- and subtotal) thyroidectomy and 40 patients having a tot
al thyroidectomy were analyzed. Patients had no more than one palpable
nodule, no cervical adenopathy and no history of previous thyroid sur
gery. An ultrasound was performed routinely within four months of surg
ery. Forty-six nodules were detected by final pathology in the partial
thyroidectomy group but only 42% were detected by palpation and 59% b
y ultrasound. The median diameter of non-palpable and ultrasound undet
ected partial thyroidectomy nodules was 0.5 cm and all were benign exc
ept for one case of lymphoma. Pathology detected 186 nodules in the to
tal thyroidectomy group although palpation only detected 22% of these
and ultrasound 42%. The median diameters of the benign and malignant n
on-palpable nodules were 0.4 cm and 0.25 cm respectively. Most of the
undetected nodules in the total thyroidectomy group were benign, but t
here were 20 non-palpable and 18 ultrasound undetected papillary carci
nomas.