HECK REACTIONS OF 3-IODO-N-METHYL-QUINOLI N-2(1H)-ONES WITH 2-METHYLBUT-3-EN-2-OL - CHEMISTRY OF NATURAL SUBSTANCES .162.

Authors
REISCH J IDING M
Citation
J. Reisch et M. Iding, HECK REACTIONS OF 3-IODO-N-METHYL-QUINOLI N-2(1H)-ONES WITH 2-METHYLBUT-3-EN-2-OL - CHEMISTRY OF NATURAL SUBSTANCES .162., Die Pharmazie, 48(8), 1993, pp. 579-582
Citations number
14
Categorie Soggetti
Pharmacology & Pharmacy",Chemistry
Journal title
Die Pharmazie → ACNP
ISSN journal
00317144
Volume
48
Issue
8
Year of publication
1993
Pages
579 - 582
Database
ISI
SICI code
0031-7144(1993)48:8<579:HRO3NW>2.0.ZU;2-W
Abstract
Treatment of 4-acetoxy-3-iod-N-methyl-quinolin-2-(1H)-one, 3-iod-N-met hyl-4-tosyloxy-quinolin-2(1H)-one and 3-iod-4-methoxy-N-methyl-quinoli n-2(1H)-one with 2-methylbut-3-en-2-ol under Heck conditions led to th e related (E)-343-methylbut-1-en-3-olyl)-derivatives, potential precur sors of dimeric quinolines. Dehydration of the tertiary hydroxy group of ethylbut-1-en-3-olyl)-N-methyl-quinolin-2-(1H)-one with acetic acid gave methylbut-1,3-dienyl)-N-methyl-quinolin-2(1H)-one.