INFLUENCE OF CYCLODEXTRINES ON THE CLEAVA GE OF NITROPHENYL ACETATES AND ESTERS OF NITROBENZOIC ACIDS

Authors
BEYRICH T GRUNERT R JIRA T
Citation
T. Beyrich et al., INFLUENCE OF CYCLODEXTRINES ON THE CLEAVA GE OF NITROPHENYL ACETATES AND ESTERS OF NITROBENZOIC ACIDS, Die Pharmazie, 48(8), 1993, pp. 597-599
Citations number
20
Categorie Soggetti
Pharmacology & Pharmacy",Chemistry
Journal title
Die Pharmazie → ACNP
ISSN journal
00317144
Volume
48
Issue
8
Year of publication
1993
Pages
597 - 599
Database
ISI
SICI code
0031-7144(1993)48:8<597:IOCOTC>2.0.ZU;2-2
Abstract
The influence of alpha-, beta- and gamma-Cyclodextrine (CD), respectiv ely, was investigated on the cleavage of stereoisomeric nitrophenyl ac etates and esters of nitrobenzoic acids. In spite of the different lip ophilicity the binding is almost of the same kind, nevertheless the CD s catalyzed the cleavage of phenolesters only. It was observed that be ta-CD inhibited the alkylesters. The stability of binding and the clea vage are distinct processes which are not necessarily connected.