MILKY SPOTS REACTION TO SCHISTOSOMAL MANSONI INFECTION

Milky spots (MS), considered by the authors as a Coelomatic Lympho-mye lopoietic Organ (CLMO), present a strong reactivity during experimenta l schistosomal mansoni infection, characterized by an increase of lymp hocytes, macrophages, plasmocytes, mast cells, neutrophils and express ion of eosinophil metaplasia. Intraperitoneal injection of purified Sc histosoma mansoni (Sm) eggs provoked a rise in the number and size of MS, which developed the sessile marginal and pedunculated types. The a uthors conclude that egg antigens are, at least partially, responsible for MS reactivity during Sm infection.