RECENT ADVANCES AND PROSPECTIVE RESEARCHES ON MOLECULAR EPIDEMIOLOGY OF DENGUE VIRUSES

Authors
Citation
V. Deubel, RECENT ADVANCES AND PROSPECTIVE RESEARCHES ON MOLECULAR EPIDEMIOLOGY OF DENGUE VIRUSES, Memorias do Instituto Oswaldo Cruz, 87, 1992, pp. 133-136
Citations number
27
Categorie Soggetti
Medicine, Research & Experimental
ISSN journal
00740276
Volume
87
Year of publication
1992
Supplement
5
Pages
133 - 136
Database
ISI
SICI code
0074-0276(1992)87:<133:RAAPRO>2.0.ZU;2-I
Abstract
The determination of amino acid changes in the envelope protein by dir ect sequencing of either genomic RNA or PCR-amplified cDNA fragments p rovides useful informations for assessing the genetic variability and the geographic distribution of the actually most widespread dengue-2 s erotype. The possible link of variations in the envelope protein-gene and virus virulence is discussed.