EFFICIENT SYNTHESIS OF ENANTIOMERICALLY PURE C-2-SYMMETRICAL DIOLS VIA THE ALLYLBORATION OF APPROPRIATE DIALDEHYDES

Authors
RAMACHANDRAN PV CHEN GM BROWN HC
Citation
Pv. Ramachandran et al., EFFICIENT SYNTHESIS OF ENANTIOMERICALLY PURE C-2-SYMMETRICAL DIOLS VIA THE ALLYLBORATION OF APPROPRIATE DIALDEHYDES, Tetrahedron letters, 38(14), 1997, pp. 2417-2420
Citations number
19
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
14
Year of publication
1997
Pages
2417 - 2420
Database
ISI
SICI code
0040-4039(1997)38:14<2417:ESOEPC>2.0.ZU;2-T
Abstract
The reaction of the enantiomers of B-allyidiisopinocampheylborane with 1,2-, 1,3-, and 1,4-benzenedialdehydes, 2,6-pyridinedicarboxaldehyde, glyoxal, and glutaric dialdehyde, provides the corresponding enantiom ers of the bis-homoallylic alcohols in 88-98% de, and greater than or equal to 98% ee. (C) 1997 Elsevier Science Ltd.