We examined data from a large cohort of homosexual and heterosexual fe
males and males concerning their siblings' sexual orientations. As in
previous studies, both male and female homosexuality were familial. Ho
mosexual females had an excess of homosexual brothers compared to hete
roxual subjects, thus providing evidence that similar familial factors
influence both male and female homosexuality. Furthermore, despite th
e large sample size, homosexual females and males did not differ signi
ficantly from each other in their proportions of either homosexual sis
ters or homosexual brothers. Thus, results were most consistent with t
he possibility that similar familial factors influence male and female
sexual orientation. However, because results conflicted with those of
some other studies, and because siblings' sexual orientations were ob
tained in a manner likely to yield more errors than in these other, sm
aller studies, further work is needed using large samples and more car
eful methods before the degree of cofamiliality of male and female hom
osexuality can be resolved definitively. We also examined whether some
parental influences comprised shared environmental effects on sexual
orientation. Scales attempting to measure such influences failed to di
stinguish subjects with homosexual siblings from subjects with only he
terosexual siblings and, thus, did not appear to measure shared enviro
nmental determinants of sexual orientation.