CHYMOTRYPSIN-CATALYZED PEPTIDE-SYNTHESIS IN ICE - USE OF UNPROTECTED AMINO-ACIDS AS ACYL ACCEPTORS

Authors
SCHUSTER M ULLMANN G ULLMANN U JAKUBKE HD
Citation
M. Schuster et al., CHYMOTRYPSIN-CATALYZED PEPTIDE-SYNTHESIS IN ICE - USE OF UNPROTECTED AMINO-ACIDS AS ACYL ACCEPTORS, Tetrahedron letters, 34(36), 1993, pp. 5701-5702
Citations number
7
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
34
Issue
36
Year of publication
1993
Pages
5701 - 5702
Database
ISI
SICI code
0040-4039(1993)34:36<5701:CPII-U>2.0.ZU;2-B
Abstract
Kinetically controlled chymotrypsin-catalyzed peptide syntheses are ca rried out using unprotected amino acids as amino components. The react ions are performed in frozen aqueous solutions. A gram scale dipeptide synthesis is described.