Synapse formation by aberrant nerves at chronically denervated intrins
ic laryngeal muscles was observed even at 21 months after the transect
ion of the recurrent laryngeal nerve in cats. Some of the aberrant ner
ves were adrenergic, and these nerve terminals were in synaptic contac
t with the postsynaptic membrane of the neuromuscular junctions togeth
er with non-adrenergic nerve terminals. Therefore, heterogeneous reinn
ervation between adrenergic nerve and muscle was found to be maintaine
d for a long time.