ESTIMATION OF DOUBLE-STRAND BREAK QUALITY BASED ON TRACK-STRUCTURE CALCULATIONS

Authors
MICHALIK V
Citation
V. Michalik, ESTIMATION OF DOUBLE-STRAND BREAK QUALITY BASED ON TRACK-STRUCTURE CALCULATIONS, Radiation and environmental biophysics, 32(3), 1993, pp. 251-258
Citations number
17
Categorie Soggetti
Biophysics,"Radiology,Nuclear Medicine & Medical Imaging","Environmental Sciences
Journal title
Radiation and environmental biophysics → ACNP
ISSN journal
0301634X
Volume
32
Issue
3
Year of publication
1993
Pages
251 - 258
Database
ISI
SICI code
0301-634X(1993)32:3<251:EODBQB>2.0.ZU;2-E
Abstract
The aim of this study was to investigate whether double-strand break ( DSB) quality is related to the complexity of radiation-induced damage or to the spatial distribution of initial DSBs. The analysis was based on track structure calculations and DNA damage modelling. The results obtained indicate that the quality of DSBs is related to their initia l spatial distribution rather than to their complexity.