HIGH-RESOLUTION MICROFLUOROMETRY OF CA2+ SIGNALING IN DENDRITES AND SPINES OF CENTRAL NEURONS

Authors
MULLER W CONNOR JA
Citation
W. Muller et Ja. Connor, HIGH-RESOLUTION MICROFLUOROMETRY OF CA2+ SIGNALING IN DENDRITES AND SPINES OF CENTRAL NEURONS, Japanese Journal of Physiology, 43, 1993, pp. 190000131-190000137
Citations number
19
Categorie Soggetti
Physiology
Journal title
Japanese Journal of Physiology → ACNP
ISSN journal
0021521X
Volume
43
Year of publication
1993
Supplement
1
Pages
190000131 - 190000137
Database
ISI
SICI code
0021-521X(1993)43:<190000131:HMOCSI>2.0.ZU;2-Z
Abstract
Using an upright microscope and an interface type slice chamber for ep ifluorometric imaging of fura-2 injected neurons in brain slice is par ticularly convenient to obtain good spatial resolution. Using this app roach we found that muscarinic activation uncouples K-channel activati on from intradendritic Ca and that postsynaptic spines represent indep endent compartments for Ca-activated processes when activated synaptic ally.