The effects of acetylcholine (ACh) and adrenaline on fast axoplasmic t
ransport of cultured superior cervical ganglion cells were analyzed wi
th a computer-assisted video-enhanced differential interference contra
st microscopic system. ACh suppressed the transport reversibly in both
anterograde and retrograde directions, and adrenaline increased the t
ransport reversibly. These effects are related to the amount of c-AMP.
This amount of c-AMP in connection with neurotransmitters controls th
e axoplasmic transport, which in tum is related to the activity of the
neuron.