VIRUS-PRODUCING SPH-7(T) LINE OBTAINED FR OM THE SPLEEN GELLS OF PAPIO-HAMADRYAS WITH MALIGNANT-LYMPHOMA

Authors
AGRBA VZ TIMANOVSKAYA VV KAKUBAVA VV ARAVIASHVILI DE INDZHIYA LV CHIKOBAVA MG GURTSEVICH VE PAVLISH OA LAPIN BA
Citation
Vz. Agrba et al., VIRUS-PRODUCING SPH-7(T) LINE OBTAINED FR OM THE SPLEEN GELLS OF PAPIO-HAMADRYAS WITH MALIGNANT-LYMPHOMA, Eksperimental'naa onkologia, 15(4), 1993, pp. 38-41
Citations number
14
Categorie Soggetti
Oncology
Journal title
Eksperimental'naa onkologia → ACNP
ISSN journal
02043564
Volume
15
Issue
4
Year of publication
1993
Pages
38 - 41
Database
ISI
SICI code
0204-3564(1993)15:4<38:VSLOFO>2.0.ZU;2-9
Abstract
T-lymphoid suspension cell line SPH-7(T) was obtained by cultivation o f mononuclear cells from the spleen of Papio hamadryas. The cells reve aled T-cell characteristics with a hepler phenotype (CD4+). The Southe rn blott-hybridization has exhibited proviral DNA groups STVL-I. Mg2+- dependent reverse transcriptase activity and polypeptides of gag-compl ex (p24 and p19) STTV-I have been found in the culture fluid using imm unoblotting with HTLV-I positive sera.