Acrodontiolamide, a new fungal metabolite has been isolated from the c
ell-free culture medium of Acrodontium salmoneum. Its purification was
achieved by centrifugal TLC on silica gel and the structural analysis
was based on spectroscopic data relative to both the natural product
and its diacetyl derivative. This secondary metabolite, identified wit
h ophenyl)-3-hydroxy-4-dichloromethoxy-isobutanamide exhibited antifun
gal properties.