SYNTHESIS OF A BIOLOGICALLY-ACTIVE CHLORINATED ANALOG OF (E,E)-8,10-DODECADIENOL (CODLEMONE)

Authors
TELLIER F HAMMOUD A RATOVELOMANANA V LINSTRUMELLE G DESCOINS C
Citation
F. Tellier et al., SYNTHESIS OF A BIOLOGICALLY-ACTIVE CHLORINATED ANALOG OF (E,E)-8,10-DODECADIENOL (CODLEMONE), Bioorganic & medicinal chemistry letters, 3(8), 1993, pp. 1629-1632
Citations number
20
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
3
Issue
8
Year of publication
1993
Pages
1629 - 1632
Database
ISI
SICI code
0960-894X(1993)3:8<1629:SOABCA>2.0.ZU;2-W
Abstract
An efficient stereoselective synthesis of a chloro analog of codlemone , based upon the palladium-catalyzed coupling reaction of functionaliz ed alkenylalanes with (E)-1,2-dichloroethylene, is described. This ana log is more active than the natural pheromone in field tests.