A NEW GALACTOSYL TRANSFERASE INHIBITOR

Citation
Rr. Schmidt et K. Frische, A NEW GALACTOSYL TRANSFERASE INHIBITOR, Bioorganic & medicinal chemistry letters, 3(8), 1993, pp. 1747-1750
Citations number
30
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
ISSN journal
0960894X
Volume
3
Issue
8
Year of publication
1993
Pages
1747 - 1750
Database
ISI
SICI code
0960-894X(1993)3:8<1747:ANGTI>2.0.ZU;2-N
Abstract
Galactal-1-yl-methylphosphonates 2a,b and uridine phosphate derivative 1 were prepared and their inhibitory activity towards beta-galactosyl transferase from bovine milk investigated. 1 exhibited strong competi ve inhibition.