FACTORS CONTRIBUTING TO REINFECTION WITH SCHISTOSOMIASIS-JAPONICA AFTER TREATMENT IN THE LAKE REGION OF CHINA

The prevalence of schistosomiasis due to S. japonicum is focally high in the lake regions of China, and reinfection after treatment with pra ziquantel is frequent. In this study, the total reinfection rate among 740 treated persons was 12.9%. Factors associated with reinfection we re age and sex, water contact and the distance from homes to snail hab itats. The reinfection rate was higher among men (15.0%) than among wo men (8.3%). The frequency of water contact is the main factor in reinf ection. Among persons with more than 120 and 10-120 water-contact days , the reinfection rates were 24.0% and 16.4%, respectively. The reinfe ction rates among people living 0 m, 500 m and 1000 m from snail-ridde n areas were 14.1%, 8.3% and 4.3%, respectively. Fishing was the most frequent reason for water-contact, followed by herding animals and pla ying in water, reinfection rates among those engaging in these activit ies were 36.4%, 16.3% and 22.9%, respectively. Reinfection is clearly a problem, and since much of it is connected with essential economic a ctivities, the cycle of infection and reinfection is not likely to be broken until effective methods for eliminating reservoirs of infection are developed.