Scaly skin alterations on the surface of the legs are frequently found
in African children. Because similar signs occur in essential fatty a
cid deficiency, the fatty acid status of a group of African children w
ith (n = 10) and without (n = 27) such skin alterations was determined
. Analysis of the fatty acid composition of the plasma phospholipid an
d cholesterol ester fractions as well as clinical examinations were pe
rformed. Constantly low levels of linoleic acid and arachidonic acid w
ere not associated with the occurrence of scaly skin alterations, whic
h were also found in children with normal values for these polyunsatur
ated fatty acids. It is suggested that scaly skin alterations in Congo
lese children are not a sign of essential fatty acid deficiency.