Five cases of artifactual In-111 leukocyte pulmonary activity were not
ed at three local hospitals in a 4-day period. Based on the difference
s in the preparation of the final indium leukocyte product, the proble
m could be attributed to the indium oxine reagent in a specific lot. T
his artifact of multiple small foci of marked increased activity in th
e lungs (clumping pattern), attributable to the In-111 oxine reagent,
has not been described previously.