Z. Manojlovic et al., QUALITATIVE-ANALYSIS OF DRUG PRESCRIPTION IN A GERIATRIC POPULATION-SAMPLE, International journal of clinical pharmacology, therapy and toxicology, 31(9), 1993, pp. 430-434
The rationality of specialist drug prescription in 154 patients older
than 64 in 3 Zagreb homes for the aged was analyzed over an 11-month p
eriod. Categories analyzed were: number of prescribed drugs, justifica
tion of prescription, adequacy of the dose, route, form and therapy du
ration of the prescribed drugs, adequacy of the type of the prescribed
drugs in the advanced age and the presence of contraindications of dr
ugs used. The criterion of the rational drug use was the WHO's modifie
d definition of rational drug therapy: ''Application of an appropriate
drug by a correct route in an adequate dose over a sufficiently long
period of time''. This basic criterion was further elaborated in relat
ion to the analyzed categories. There were 2.66 (+/- 1.65) prescribed
drugs per visit in which drugs were prescribed. In all analyzed catego
ries, distinctive aberations from the principles of rational drug pres
cription were found. One hundred and sixty-four (41.4%) of all drugs w
ere unjustifiably prescribed and 103 (26.4%) were not dosed correctly.
The duration of the therapy was inadequate for 60 (15.4%), route for
41 (10.5%), form for 32 (8.2%) of drugs prescribed. Seventy-five (19.3
%) were not adequate because of patients' age and 15 (3.9%) were presc
ribed in spite of existing contraindications.