THE IMPORTANCE OF ANESTHESIA (FENTANYL, D IAZEPAM AND DROPERIDOL VERSUS KETAMIN AS WELL AS PENTOBARBITAL) FOR THE TOTAL CLEARANCES OF CR-51EDTA AND I-125 HIPPURAN IN THE RAT

Authors
GELLERT S DEVAUX S MICHEL P
Citation
S. Gellert et al., THE IMPORTANCE OF ANESTHESIA (FENTANYL, D IAZEPAM AND DROPERIDOL VERSUS KETAMIN AS WELL AS PENTOBARBITAL) FOR THE TOTAL CLEARANCES OF CR-51EDTA AND I-125 HIPPURAN IN THE RAT, Nieren- und Hochdruckkrankheiten, 22(8), 1993, pp. 406-411
Citations number
NO
Categorie Soggetti
Urology & Nephrology
Journal title
Nieren- und Hochdruckkrankheiten → ACNP
ISSN journal
03005224
Volume
22
Issue
8
Year of publication
1993
Pages
406 - 411
Database
ISI
SICI code
0300-5224(1993)22:8<406:TIOA(D>2.0.ZU;2-4
Abstract
In a comparative investigation with fentanyl, diazepam and droperidol vs. ketamin or pentobarbital in male wistar rats we found the best cle arance results under the anaesthesia with pentobarbital. The Cr-51-EDT A-clearance for the determination of the glomerular filtration rate (G FR) was 1 +/- 0.13, the I-125-hippuran-clearance for the determination of the effective renal plasma flow (ERPF) was 2.93 +/- 0.508 ml/min/1 00 g body weight (BW). After uninephrectomy the function of the remain ing kidney arised to nearly 70% of two kidneys.