EXPERIENCES ON THE EFFECTIVENESS OF AN IN TRAMAMMARY INFUSION WITHOUTCONTAINING ANTIBIOTICS .4. INNOCUITY TEST OF THE NEW INTRAMAMMARY INFUSION

Effect of the therapeutical and trine doses of the soft, propolis-cont aining intramammary infusion (Provet(R) A.U.V., Apipharma) was studied in 6 each healthy cows. Trends of the temperature of udder skin, as w ell as electric conductivity, somatic cell counts and chloridion conce ntrations were compared in 4 milk samples collected before, in 6 milk samples collected during and in 12 milk samples collected after the tr eatment (Table 1). It was found that Provet infusion did not modified the temperature of udder skin. It increased the electric conductivity of milk within the physiologic limit values even after the treatment. Chloridion concentration of the milk increased also due to the propoli s, however it did not exceed the physiologic limit value (Table 2). Th e most significant increase was observed in case of the somatic cell c ounts, the cell counts were well over the 500 000 limit value even dur ing 6 days after the treatment (Figures 1 and 2). During the eliminati on dynamic measurements, measurable traces of the medicament could not be detected by thin-layer chromatography (detection limit: 30 mug/l), suitable for the demonstration of propolis.