A GENERAL AND SIMPLE REMOVAL OF THE ALLYLOXYCARBONYL PROTECTING GROUPBY PALLADIUM-CATALYZED REACTIONS USING NITROGEN AND SULFUR NUCLEOPHILES

Authors
GENET JP BLART E SAVIGNAC M LEMEUNE S LEMAIREAUDOIRE S BERNARD JM
Citation
Jp. Genet et al., A GENERAL AND SIMPLE REMOVAL OF THE ALLYLOXYCARBONYL PROTECTING GROUPBY PALLADIUM-CATALYZED REACTIONS USING NITROGEN AND SULFUR NUCLEOPHILES, Synlett, (9), 1993, pp. 680-682
Citations number
22
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
9
Year of publication
1993
Pages
680 - 682
Database
ISI
SICI code
0936-5214(1993):9<680:AGASRO>2.0.ZU;2-R
Abstract
Smooth removal of the Allyloxycarbonyl (Alloc) moiety from allylic est ers, carbamates and carbonates is carried out by Pd (0) catalyzed ally l transfer to diethylamine and thio derivatives as the accepting nucle ophiles. The method has been successfully used for selective deprotect ion of secondary amines and base sensitive substrates.