A 32-year-old man presented to the accident & emergency (A&E) departme
nt complaining of an inability to use his left arm and shoulder. The p
revious day he had injected heroin intravenously into his left antecub
ital vein. Examination revealed signs of a left-sided brachial plexus
lesion. There was no history or sign of trauma. Neurological investiga
tion revealed motor and sensory loss compatible with a complete brachi
al plexus lesion. He exhibited a very rare condition, asymmetrical atr
aumatic brachial plexopathy, thought to result from an inflammatory ca
use, which not only affects the brachial, but also other plexi or indi
vidual nerves in the body and thought to be related to repeated intrav
enous use of heroin. This is a condition for which there is no specifi
c treatment but which usually resolves spontaneously in the absence of
continuing heroin n-misuse.