A large, cross-sectional aging investigation of performance on the Str
oop Color-Word Test (SCWT) was carried out. Subjects were 247 voluntee
rs, ages 20-80 in seven age levels. Although all subjects thought them
selves to be normal and healthy, a post hoc division could be made on
the basis of biological life events (BLE). BLE are mild biological or
environmental factors, such as repeated experiences of general anesthe
sia, that can hamper optimal brain functioning. Apart from the anticip
ated age effects, performance was poorer in subjects who had experienc
ed one or more BLE: The slowing due to BLE was comparable to the effec
t of age, especially on the task involving language interference in co
lor-naming. Education had a significant effect on performance: More hi
ghly educated subjects performed better than less educated subjects. N
o sex differences were observed. These findings replicate observations
made with other tests in parallel studies. They are also in line with
several other studies reporting interactions between the effects of a
ging and physical fitness. This study questions some of the validity o
f cognitive aging research, as our data suggest that screening for BLE
as age-extrinsic factors in nondiseased subjects can reduce many of t
he performance deficits usually ascribed to aging per se.