M. Iacoangeli et al., STAGING OF SUPRATENTORIAL HEMISPHERIC GLIOMA USING TUMOR EXTENSION, HISTOPATHOLOGICAL GRADE AND EXTENT OF SURGICAL RESECTION, British Journal of Surgery, 80(9), 1993, pp. 1130-1133
A 'TGS' classification for supratentorial brain glioma is proposed, ba
sed on three parameters: tumour extension (T), histopathological grade
(G) and extent of surgical resection (S). Two groups of patients were
analysed: the first (n = 137) had tumour submitted to stereotactic bi
opsy; the second (n = 60) had malignant glioma operated on by cranioto
my and tumour resection. All three staging parameters significantly in
fluenced survival. Histopathological grade was the most significant fa
ctor, and the only independent variable on multivariate analysis, foll
owed by extent of tumour and then extent of surgical resection. The da
ta support the applicability of the proposed parameters for a staging
classification of hemispheric brain glioma.