PROTEIN ENGINEERING AS A TOOL FOR UNDERSTANDING ELECTRON-TRANSFER

Authors
WUTTKE DS GRAY HB
Citation
Ds. Wuttke et Hb. Gray, PROTEIN ENGINEERING AS A TOOL FOR UNDERSTANDING ELECTRON-TRANSFER, Current opinion in structural biology, 3(4), 1993, pp. 555-563
Citations number
72
Categorie Soggetti
Biology
Journal title
Current opinion in structural biology → ACNP
ISSN journal
0959440X
Volume
3
Issue
4
Year of publication
1993
Pages
555 - 563
Database
ISI
SICI code
0959-440X(1993)3:4<555:PEAATF>2.0.ZU;2-Y
Abstract
The ability to engineer proteins in a specific manner is a powerful to ol when applied to the study of biological electron transfer. Mutagene sis, semisynthesis, and site-specific modification have been employed to prepare novel electron-transfer proteins- theoretical and experimen tal work on these proteins has elucidated the factors that tune active -site redox potentials and spectroscopic features as well as the prope rties that control electron transfer through polypeptide structures.