We have examined the use of different pre-surgical analgesic technique
s in 30 children aged 2-10 yr undergoing repair of hypospadias. They w
ere allocated randomly, in a double-blind, placebo-controlled study, t
o receive one of three analgesic techniques (n = 10): lumbar extradura
l analgesia using 0.5 % bupivacaine 1 mg kg-1 plus morphine 50 mug kg-
1; morphine 100 mug kg-1 im.; or subpubic block using 0.5 % bupivacain
e 0.5 mg kg-1 for each side. Analgesics were given after induction of
anaesthesia and before the start of sur ery. Children given extradural
analgesia had more stable haemodynamic variables and smaller catechol
amine concentrations and needed less anaesthetic supplementation, with
no analgesic requirement in the postoperative period. Nausea or vomit
ing were not reported in children given subpubic block.