Background. Malignant glaucoma (ciliary block glaucoma; aqueous misdir
ection glaucoma) is an incompletely understood, rare and serious compl
ication of intraocular surgery. Methods: A woman with pseudophakic mal
ignant glaucoma underwent successful neodymium:YAG (Nd:YAG) laser phot
odisruption of the anterior hyaloid face with resolution of the glauco
ma. High-resolution ultrasound biomicroscopy was used to image the ant
erior segment and anterior chamber angle before and after laser surger
y. Results: Ultrasound biomicroscopy provided cross-sectional images o
f the iris, posterior chamber intraocular lens (IOL), and ciliary body
and their relative positions before and after resolution of the malig
nant glaucoma. Anterior rotation of the ciliary body and anterior cham
ber shallowing normalized after rupture of the anterior hyaloid face.
Conclusion: High-resolution ultrasound biomicroscopy provided images c
onsistent with accepted concepts of the pathophysiology of this diseas
e and offers great promise for the future elucidation of the anatomic
mechanisms underlying various forms of glaucoma.