Patients with venous leg ulcers have a readily recognized clinical syn
drome of shallow ulcers, oedema, leg pain, venous ankle blush, lipoder
matosclerosis, varicose veins, hyperpigmentation, and atrophie blanche
, and they are assumed to have venous abnormalities. We examined 43 pa
tients with venous leg ulcers, and compared those with obvious venous
abnormalities (defined as historical or clinical evidence of deep veno
us thrombosis or varicose veins) with those with presumed venous abnor
malities (defined as lacking any such evidence), to see if they presen
ted with different clinical features. We found that both groups had si
milar clinical features, with the exception that lipodermatosclerosis
was present more frequently in those patients with obvious venous abno
rmalities (94 vs. 36%, P < 0.001). Most patients with presumed venous
abnormalities had musculoskeletal conditions which might cause calf pu
mp dysfunction (91%). Using air plethysmography, we were unable to con
firm that all patients with presumed venous abnormalities did have int
rinsic venous abnormalities. We propose that ulcers occurring in this
clinical syndrome be designated as calf pump dysfunction ulcers (CPD u
lcers), rather than venous ulcers.