STIMULATION OF GROWTH OF CANDIDA-GUILLIERMONDII AND STREPTOCOCCUS-FAECALIS BY SEROTONIN

Periodic addition of serotonin to the culture medium during growth of the yeast Candida guilliermondii and the bacterium Streptoccus faecali s has a stimulating effect on growth of these cultures. The effect is manifested as activation of cell multiplication in the lag phase, acce lerated passage of the cultures through the logarithmic phase of growt h, and the more rapid reaching of the stationary phase. Addition of se rotonin at intervals of 2 h to the growth medium in a concentration of 10(-7) M provided optimal conditions for realization of its stimulati ng action.