Extraction of the aerial parts of Ophiorrhiza cf. ferruginea (Rubiacea
e) has yielded the tertiary indole alkaloids dihydrocycloakagerine (1)
, 3,14-dihydrodecussine (mostuenine) (3) and tetrahydroakagerine (4),
and the quaternary indole alkaloid isomalindine (5). The structures of
dihydrocycloakagerine (1) and isomalindine (5) are confirmed by the X
-ray method.