SYNTHESIS OF SOME BENZOB!1,6!NAPHTHYRIDINES AND BENZOB!1,7!NAPHTHYRIDINES

Authors
CHEN QP DEADY LW
Citation
Qp. Chen et Lw. Deady, SYNTHESIS OF SOME BENZOB!1,6!NAPHTHYRIDINES AND BENZOB!1,7!NAPHTHYRIDINES, Australian Journal of Chemistry, 46(7), 1993, pp. 987-993
Citations number
11
Categorie Soggetti
Chemistry
Journal title
Australian Journal of Chemistry → ACNP
ISSN journal
00049425
Volume
46
Issue
7
Year of publication
1993
Pages
987 - 993
Database
ISI
SICI code
0004-9425(1993)46:7<987:SOSBAB>2.0.ZU;2-T
Abstract
Pfitzinger (1-benzylpiperidin-4-one with 7-methylisatin) and Friedland er (3-aminopyridine-4-carbaldehyde with 2-methylcyclohexanone) synthes es, respectively, were used to prepare the title 'azaacridines' contai ning a methyl substituent peri to the central nitrogen. Oxidation of t his group gave the corresponding.aldehyde and carboxylic acid. In the 1,6! case, especially, the 10-position was also easily oxidized to gi ve acridone analogues. Nitration occurred exclusively in the benzenoid rings.