PRIMARY CENTRAL WHITE-MATTER DEGENERATION IN OLD DOGS

Citation
I. Ferrer et al., PRIMARY CENTRAL WHITE-MATTER DEGENERATION IN OLD DOGS, Acta Neuropathologica, 86(2), 1993, pp. 172-175
Citations number
20
Categorie Soggetti
Neurosciences
Journal title
ISSN journal
00016322
Volume
86
Issue
2
Year of publication
1993
Pages
172 - 175
Database
ISI
SICI code
0001-6322(1993)86:2<172:PCWDIO>2.0.ZU;2-5
Abstract
Degeneration of the central white matter is described in old dogs. The presence of ubiquitin-immunoreactive free granules and intracytoplasm ic globules in glial cells and macrophages, together with galactocereb roside-immunoreactive precipitates and lipofuscin storage, point to th e likelihood of a primary myelin degeneration with deposits of non-deg raded ubiquitin-protein conjugates and complex galactolipids.