A. Wohlfarth et al., IDENTIFICATION OF N-DELTA-ACETYLORNITHINE AS A NOVEL OSMOLYTE IN SOMEGRAM-POSITIVE HALOPHILIC EUBACTERIA, Applied microbiology and biotechnology, 39(4-5), 1993, pp. 568-573
In the course of a screening programme for novel natural substances ac
ting as compatible solutes, an unusual amino acid derivative was detec
ted in several halophilic Gram-positive eubacteria. The compound was i
solated and subsequently identified as N(delta)-acetylornithine using
spectroscopic (NMR, MS) and chromatographic methods. So far, N(delta)-
acetylornithine has only been described as an excretion product of som
e bacteria under certain growth conditions. This report describes, for
the first time, its intracellular accumulation and use as a compatibl
e solute in halophilic/halotolerant eubacteria.