Tr. Guilarte, VITAMIN-B6 AND COGNITIVE-DEVELOPMENT - RECENT RESEARCH FINDINGS FROM HUMAN AND ANIMAL STUDIES, Nutrition reviews, 51(7), 1993, pp. 193-198
Numerous studies have suggested that pregnant and lactating women may
have dietary intakes of vitamin B6 that are well below the recommended
dietary allowance, which may affect the vitamin B6 status of their of
fspring. This nutrient is an essential cofactor in the developing cent
ral nervous system and may influence brain development and cognitive f
unction. Recent work in animal models suggests that vitamin B6 deficie
ncy during gestation and lactation alters the function of N-methyl-D-a
spartate receptors, a subtype of receptors of the glutamatergic neurot
ransmitter system thought to play an important role in learning and me
mory.