Biopsy and autopsy protocols revealed that between 1972 and 1981, 85 c
ases of scleroma were diagnosed in Uganda. The disease was found to af
fect females more than males, and was found to be more common in the m
iddle aged. Scleroma occurred in the nose in 96% of cases and presente
d commonly at a late stage. The disease was found commonly among the t
ribes of south western Uganda and Itesot in the east. Possible factors
associated with the distribution of this disease in Uganda are discus
sed.