STUDIES ON HALOQUINOLINES .1. SYNTHESIS AND CHARACTERIZATION OF SUBSTITUTED HALOQUINOLINES

Authors
RAO DM GIRIDHAR T REDDY RB MOULI GVPC
Citation
Dm. Rao et al., STUDIES ON HALOQUINOLINES .1. SYNTHESIS AND CHARACTERIZATION OF SUBSTITUTED HALOQUINOLINES, Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry, 36(1), 1997, pp. 29-32
Citations number
6
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry → ACNP
ISSN journal
03764699
Volume
36
Issue
1
Year of publication
1997
Pages
29 - 32
Database
ISI
SICI code
0376-4699(1997)36:1<29:SOH.SA>2.0.ZU;2-E
Abstract
Condensation reaction of halogenated anilines with ethyl acetoacetate affords quinoline 1,2,3. The compound 1 is coupled with benzenediazoni um chloride and then reduced to furnish 3-amino-quinoline 5 which unde rgoes cyclisation with carbon disulphide to give the mercaptooxazolo[4 ,5-c]-quinoline 6a. The reaction of 6a with RX produces the substitute d mercapto derivatives 6b-m. The compounds have been characterised by their analytical and spectral data.