SYNTHESIS AND ANTIINFLAMMATORY ACTIVITY OF SOME NEW INDOLE AND INDAZOLE DERIVATIVES

Authors
AMIR M DHAR N TIWARI SK
Citation
M. Amir et al., SYNTHESIS AND ANTIINFLAMMATORY ACTIVITY OF SOME NEW INDOLE AND INDAZOLE DERIVATIVES, Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry, 36(1), 1997, pp. 96-98
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry → ACNP
ISSN journal
03764699
Volume
36
Issue
1
Year of publication
1997
Pages
96 - 98
Database
ISI
SICI code
0376-4699(1997)36:1<96:SAAAOS>2.0.ZU;2-#
Abstract
A number of indole and indazole derivatives have been synthesized and evaluated for their anti-inflammatory activity. The tested compounds s how 31.6 to 17.1% inhibition at 100 mg/kg dose compared, to indomethac in which shows 32.3% inhibition at 50 mg/ kg dose in carrageenin induc ed paw edema in rats.