S. Saxena et al., LENS THICKNESS AXIAL LENGTH FACTOR - AN INDEX FOR BIOMETRIC ASSESSMENT OF THE EYE IN PRIMARY ANGLE-CLOSURE GLAUCOMA, Annals of ophthalmology. Glaucoma, 29(1), 1997, pp. 23-26
The first tertiary care center-based, case-control study was undertake
n to quantitate the changes occurring in 41 eyes of 41 patients with p
rimary angle-closure glaucoma, using the lens thickness/axial length f
actor. The mean lens thickness (+/- SD) and the mean ocular axial leng
th (+/- SD) for the cases and the controls were 4.61 mm (+/- 0.29), 21
.40 mm (+/- 0.75) and 4.33 (+/- 0.29), 22.92 mm (+/- 0.45), respective
ly (P < 0.001). The mean lens thickness/axial length factor for the ca
ses and the controls was 2.16 (+/- 0.16) and 1.89 (+/- 0.13), respecti
vely (P < 0.001). A combination of increased lens thickness and shorte
ned ocular axial length is an important precipitating factor in primar
y angle-closure glaucoma, and it may be useful in identifying eyes tha
t are most likely to develop the disease.