A STUDY FROM SOUTH-INDIA ON THE ASSOCIATION BETWEEN THE PAPILLOMA-VIRUS AND CARCINOMA OF THE PENIS

Specimens from 39 cases of squamous cell carcinoma of the penis were t reated for the papilloma virus using the bovine papilloma virus antibo dy and the peroxidase-antiperoxidase technique. All 39 cases showed a viral antigen situated intranuclearly, intracytoplasmically or both in tranuclearly and intracytoplasmically. No correlation could be seen be tween the presence of viral antigen and age of patient, duration of le sion, cell morphology and histological grade. The adjacent mucosa and skin were used as controls and showed no viral antigen. The inflammato ry infiltrate was dense and predominantly ''T'' lymphocyte in type. (C ) 1993 Wiley-Liss, Inc.