GIANT NONFUNCTIONING ISLET-CELL TUMOR REQUIRING PANCREATICODUODENECTOMY AND COMPLETE LIVER REVASCULARIZATION

Pancreaticoduodenectomy with revascularization of the hepatic artery a nd portal vein was performed on a 17-year-old girl with giant nonfunct ioning islet cell tumor of the pancreas. She had a remote history of n eonatal hypoglycemia leading to mental retardation and a right Wilms' tumor resected at 8 months. Serum pancreatic polypeptide levels were e levated. Her postoperative course was complicated by an ischemic perfo ration of the colon, which did not infect her prosthetic vascular graf ts. The relationship between her neonatal hypoglycemia, Wilms' tumor, and subsequent islet cell neoplasm is unclear. (C) 1993 Wiley-Liss, In c.