B. Shaikh et Wa. Moats, LIQUID-CHROMATOGRAPHIC ANALYSIS OF ANTIBACTERIAL DRUG RESIDUES IN FOOD-PRODUCTS OF ANIMAL ORIGIN, Journal of chromatography, 643(1-2), 1993, pp. 369-378
This paper reviews recent developments in the liquid chromatographic (
LC) methods of analysis for the residues of antibiotics (aminoglycosid
es, chloramphenicol, sulfonamides, tetracyclines, macrolides, beta-lac
tams, etc.) in food products of animal origin. The review also covers
clean-up procedures, such as, ultrafiltration, liquid-liquid partition
. solid-phase extraction. immunoaffinity, and matrix solid-phase dispe
rsion, for use as extraction, deproteination, and concentration steps.
The LC methods offer considerable potential for rapid automated analy
sis, and some may be used as direct screening for residues in meat and
milk.