Background. Cholecystectomy remains the best treatment for acute chole
cystitis but may cause high morbidity or mortality in critically ill o
r elderly patients. Methods. We report a retrospective study of ultras
onography-guided percutaneous cholecystostomy (USGPC) performed betwee
n 1988 and 1994 in 41 patients (mean age, 77.8 years; range, 42-95 yea
rs) as an alternative surgery. Results. Five patients (12.2%) died in
the hospital, four (9.8%) subsequently underwent operation without com
plications, six (15%) had a recurrence of cholecystitis between 3 and
24 months after withdrawal of drainage, and 26 patients are cured with
out recurrence after a mean follow-up of 33 months (range, 3-67 months
). Conclusions. USGPC appears to be the treatment of choice for high-r
isk patients, especially those with postoperative cholecystitis, sever
e acute calculous pancreatitis, or total parenteral nutrition.